Demo: Reclaim Your Time with the Automated HID NIMBUS Presto QNA System
Demand for forensic DNA sample processing is increasing, yet the hours in the day remain constant. Learn how you can process more samples in less time. The recently launched HID NIMBUS Presto QNA System is an automated set-up-and-go solution that streamlines the forensic DNA analysis workflow. This compact system combines multiple workflow steps onto one instrument, including nucleic acid purification, quantification plate setup, dilution protocol calculation for normalization, and amplification plate setup. With its easy-to-use software, this automation technology optimizes productivity, provides accurate repeatability, enabling you to achieve high-quality results in less time and with less effort. With the HID NIMBUS Presto QNA, you can minimize the time spent at the workbench, allowing you to keep data coming and dedicate more time to analysis. Join us to learn more about how the HID NIMBUS Presto QNA can streamline your forensic laboratory workflow and maximize your productivity.
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[MUSIC PLAYING]
Hello.
I'm Dave Jackson, the Senior Manager of Application
Scientists for HID here in North America.
You might remember me from HID's 2022
when I took you on a tour of our pleasantant site
and introduced you to the then new HID Nimbus Presto automated
purification system.
And that was wonderful to do with you back then.
Picking up where we left off in those flashback videos,
I'm pleased to share with you additional capabilities
that Han mentioned back in 2022.
That is the addition of automated quantitation
setup, normalization, and amplification setup
all in the one instrument.
And that is the HID Nimbus Presto QNA.
With this instrument, labs can save valuable time,
experience consistency from sample to sample and analyst
to analyst, and benefit from the quality and support
that they've come to expect from thermofisher scientific
throughout many years.
Now, this session has been recorded
prior to the release of the instrument itself.
And not many people have seen the instrument in action.
And I get the privilege of being the person
to unveil the HID Nimbus Presto QNA to one of our North
America customer labs so that they can hear firsthand
how it works, and I can glean from them
their initial impressions.
And so with that in mind, I'm really pleased to introduce
to you two of the criminalists from the San Mateo County
Sheriff's Office Crime Laboratory,
Matt Cindy and Kimberly.
Welcome Cindy and Kimberly.
It's great to have you with me.
Thank you for having us.
Cindy, I wonder if, first of all,
you can just tell me a little of your history of why
and how long you've been at the crime lab there in San Mateo.
I have been with the San Mateo County Sheriff's Office
for 24 years now.
I am a senior DNA criminalist, and I
have full response to crime scenes.
And we are looking forward to having our Nimbus Presto up
and running.
So a lot of experience in all of your years there
with the crime lab in San Mateo.
I'm really grateful for you joining me today.
And I'm very excited to show you that.
Kimberly, it's good to see you two.
Welcome.
Thank you, Dave.
We've gone back a long way, but I
wonder for everybody's sake if you would let me know a little
of your history, where you've come from,
and what you're looking forward to today.
Sure.
I have been with the crime lab here for almost four years
prior to coming to San Mateo crime lab.
I was a DNA analyst at the San Francisco Police
Department Crime Lab, which is where Dave and I met
for the first time.
And both there and here I am a--
like Cindy, a senior criminalist as well in the DNA units
and also respond to crime scenes.
Great.
Well, again, ladies, thank you very much for joining me today.
Wonder before I get started with showing you
what is capable through our new instrument.
If I could ask you just a couple of things first
about your workflow in your lab situation, perhaps, first
of all, you could let me know what some of the pains or bottlenecks
are that you experience in your case workflow.
I can go first.
We only have four criminalists who are trained and able to do
sexual assault kit DNA testing at this time.
So sexual assault kits, as we all know,
take a lot of time and energy and it is our bottleneck.
We can only do a certain number of samples in a batch.
We pretty much do everything by hand
except for the actual extraction and digest.
Thank you.
I guess that should take-- or it does take you quite a bit of time
to do all of that manual processing of your samples.
Yeah.
And I'll also add we are doing a lot of manual pipetting.
I mean, if we don't have heart threats now,
we might have it later.
So preparing a 96-well quant plate
or normalizing our samples manually and again,
preparing another 96-well plate for those two steps
in the DNA analysis process.
And those just itself take so much time
versus working soon, hopefully, with a robotics liquid handling
instrument that can take that time away from us.
We can focus on other things, like finishing writing a report
or interpreting data for a different case.
So that is definitely what I look forward to
is the ability for this instrument to help us multitask
and work on something else that needs our analysts' eyes
while the instrument is at the same time running samples for us.
So I look forward to that so much.
And so does my wrists at hand.
Madge and Kimberly, I can imagine.
And you've gotten right to the crux of the issue.
There really is the time savings that an instrument like this
can provide to you.
Cindy, are there any other thoughts about what you might want
to use the rest of your saved time for within the work
and the duties that you have in your crime life?
When we have the robotic online, it will save us a lot of stress,
really.
That's what I'm looking forward to,
because we'd be able to do so many more samples,
not have the physical difficulty of manual labor.
I can imagine that makes a big difference for sure.
When you use on software, how important is that software
interface to the work that you're doing in the various
workflows within your laboratory?
I can go first, because I am not.
Anybody good to ask you, I am not computer savvy at all.
So it needs to be pressed this button, then this button.
There it is, print.
That's how simple I need it to be.
I want to spend my time on the cases, like what I'm here to do.
I'm here to work these cases, to evaluate the data, write the
report, test of phy in court, help with training.
So an easiest software for me is, oh my gosh, I love it.
OK, that's great to hear.
What about you, Cindy?
You know, I just think we should utilize technology for what
it can do.
We have been stuck in the dark ages using Excel, spreadsheets,
and then exporting that data.
And that's so 20 years ago.
So why aren't we utilizing technology to make things easier
for us so that we can focus to the core of our job, which is
analyzing evidence to develop DNA profiles?
Wonderful.
Well, listen, again, I'm so pleased you're with me today,
because what I want to show you is perhaps something that will
address those concerns, those time-saving efforts, those
plug-and-play software topics that you brought up,
Kimberly as well, all contained within the HIV
Nimbus Presto Q&A system, which really does offer efficient
purification of nucleic acids from laced samples, automated
quant and amplification set up, as well as the automatic
normalization of your DNA samples as well.
And it's specifically scripted and optimized and validated
with our that being applied by systems, industry-leading kits
for use and forensic labs like yours.
In addition to all of that, and I'm about to show it to you,
it has a really easy-to-use software interface,
and to cap it all off, it's installed and supported by
Thermafisher scientific directly through our global
support team.
So that's what I'm excited to show you today, and I really
appreciate you sharing those topics with me and answering some
of my questions to get an idea of where you're at and what it
is that this might be able to do for you.
So I know that you already have these instruments in their
first iteration in your laboratory in order to do the
automated purification process.
And so I'm pleased about that, thrilled that you've got that.
And what I wanted to do with you today is walk you through the
new software that combines all of those portions of the workflow
that I've talked about through quantification, normalization
and amplification, in addition to the purification that you're
already familiar with because of the validation of your current
HID and MBSPresto systems in your laboratory.
So are you ready for me to let you have a look at this together
right now?
Sneak Peak, I love it.
What I've got up in front of me is the welcome screen to the
interface of this software that will be your real centerpiece
of all that will walk you through each of the different
workflows that are necessary for what we're going to look at today
and what the instrument is going to be capable of.
Your purification workflow is available through this simple
dropdown starter menu.
And from that, what you can do is drop down in this kit
selection area where you have two kits available to you that
are our kits for your use.
The PrEP file and the PrEP file are BTA extraction kit.
The BTA kit, of course, is there for more challenging samples.
The bone, the tooth enamel being the BTA acronym there.
But for those samples that you might have a protocol
validated for if you're to use that kit, today for the
benefits and the purposes of this demonstration, I'm going to
just choose the regular PrEP file or extraction kit.
And then finally, before we get into the meat of it, you must
enter a user name.
And so for today, I'm just going to put my initials in there
which are not DD, they're DJ.
So we'll enter that and click continue.
First thing to do is acknowledge that you're wanting to make
some edits to this by clicking that button that's at the
bottom and in the center so that you can tell the system that
you're going to make edits that will be tracked and logged
so that you can have an audit trail and some files generated
for troubleshooting should they need to be used in that
regard downstream.
So we will click that and then you can start choosing things
such as your input lab software, so your lice samples.
What are you going to put them into the purification
process from?
You have a choice of tubes, the Kingfisher, Deepwell plate
or a spin and filter 96 well plate.
And so for today, I'm just going to choose the tubes as an
input labware for those samples.
And then when the samples are purified, you can choose what
you want them to be alluded into, what you want those samples
to be deposited into.
So just to make this interesting, let me pick from a menu that
gives you these three options and put them into a Kingfisher
Deepwell plate.
Next, you can choose the sample volume that you're going to
begin the purification of those samples.
We'll leave it with 300 microliters for now and move
over to your illusion volume.
You get to choose how much you want to have as a volume in
your element.
So it's set here for 60 microliters.
You can go anywhere down to 20.
If you go below 35, we suggest that you have some extra
validation studies done, but anything up to larger volumes
of 290 there.
So ladies, what would be an illusion volume that you'd like
me to set this at?
25.
25.
All right, we're going low for 25.
And we just slide that down to 25 there.
And you can see that is set.
Now, the next thing to do is to tell the instrument where
your samples are and what they are in these tubes.
So you can either do one of two things.
You can choose this auto generator work list sample and
simply tell the system that you've got anything up to
96 samples to work on here.
And it will just number them one through 96 and give you a
generic work list to work with.
Or you can preload or you can load the pre-prepared
work list by choosing an Excel file that has the sample
numbers in them and details of those samples.
And for the sake of today, what I'm going to do is choose a
work list that was readied for this demonstration that has
96 samples in it by choosing that from a navigation
menu here, opening it and it will load it directly into the
system.
Now, before I move on, there's a couple of other
buttons here that you might want to consider using.
The barcode scan button, if you were to check this and turn
it on, has capabilities of checking against barcode
information that are attached to your samples or the plates
that are being used in this.
All prompt in you to do that and create those files.
We'll not turn that on today, but that's something we can
easily work with you in helping you understand and
utilize for tracking of samples.
And this checking reagent volume button as well, which just
adds another five minutes or so to the entire process and
allows the instrument to go through and do a double check
that the right volumes of reagents are in the right
places before you press start on your process for
purification.
Again, we'll leave that off for today because this
demonstration piece of software is not attached to an
actual instrument, so it would hinder us from moving
forward, but that's what that is there for.
And then finally, at the bottom here, you'll see a run
recovery menu.
And this is in case you have some kind of catastrophic event
happening, you'll have maybe the power goes off, something
happens that was unexpected, and you need to start again
from a particular point in the process.
You can easily just open up this dropdown menu, and these
will become obvious as to what these steps are as you work
through the process, but you can go back to any of these
steps that were part of the purification process and take
that sample set and start again at that point so that you're
not losing your samples should you have something, as I said,
like a power outage while you're working through the
processing.
If you need to go right back to the original Kingfisher
presto step, then this would be the button you pressed there.
So here's where it gets exciting.
We save that, and then we simply press Continue.
And Continue takes us on to the next page, which is a
schematic on the top there of the deck of the instrument, and
then some details about what you're going to put where on
that deck.
And I love this page because it makes it really easy.
It's intuitive to see where things are.
If you hover over any of these numbers that are on the deck
schematic, it'll show you a photograph and tell you what
that is and what to do sometimes such as turning on the Kingfisher
presto system.
Looking here to the tip, comb, and the illusion plate
position there on the Kingfisher presto.
If I move over here to 12A, for example, it tells you to
load a deep well plate there and label it with Wash A1.
So, and that's an important point.
Some of these plate positions have suggestions that you should
label them, and we would recommend that you do that so
that if anything wouldn't need troubleshooting down the road,
we could easily ask for those files from you, and we could
see what plates were in which positions when something might
need to be dealt with.
But that's the schematic of the deck layout of the instrument,
but the schematic itself labels each one of these
positions with numbers.
And those are really important because when you're putting
on to the deck, that which you need to do the purification of
these 96 samples that you've put in through your work list,
you can simply go to this Wash buffer A, which says that it
needs to be entered into position 7C.
And here's the trough.
If you hover over 7C, it's a 200 mil trough, and you can add
92 mils of Wash buffer A into position trough 7C.
Isopropanol here.
It's necessary if you see this, when you click on it in
position 9B, it flatches on the corresponding chart here to
the right hand side.
Position 9 is this on the deck layout where you see the
various troughs that are necessary for the reagents that
go into your purification process.
Similarly, in 9E, there's a trough that will contain Wash
buffer B, and there you need 38 mils of Wash buffer B.
And then in the F position of position 9, that trough will
contain 7 mils.
In this example of elution buffer.
Now, moving on to the tube adapter that is in position 10
here, this is where you're going to add your magnetic
particles.
And it tells you here that you're going to need 466
microliters of those magnetic particles per tube.
You can see that again by hovering over that adapter
photograph, what that position looks like on the deck and
within that tube adapter tube.
And that's where you would add those particles at that
volume per tube.
One other great feature of this screen is that if you need
some extra guidance on that, you can click on this guidance
mode button.
I'm not going to do it now because it takes you through
various videos of each one of these areas of the deck.
About 20 seconds or so long for each one, and you'll work
your way through them so that it's a step-by-step video
guide for extra clarity on how and where you put the
various components, reagents, on this deck, step-by-step,
as I say.
And then finally, you have your tip requirements in the top
right here.
Position 8 for your 1 mil filtered tips.
There's three areas.
You can put those tips there.
And you need at least 216 of those to perform the
purification of these 96 samples that you've put in here.
And 96 of the 300 microlitre filtered tips in position 11
here on the deck.
So that's how you set up the system for what you're
asking it to do with the purification of those 96
samples that you've put in through that work list.
And from here, you simply click Continue, and it will ask
you to verify the tips and the correct positions.
And then press Start, and it will begin the instrument
protocol of purifying your samples into your 25 microlitre
illusion that you've asked it to.
And so I hope that that for the purification portion of it
is clear and easy.
And wonder what your feedback or understanding of that is if
you have any questions of that, Kimberly or Cindy.
Do I have a question for you, Dave?
So if you have less tips than what it's asking or less
the agent than what is listed, will it let you know?
Or will it pause during the run to let you know?
And the post during the run, this is all to be set up ahead
of time.
And so you need to verify on the next screen that you have
the correct amount of tips.
And you'll show the instrument where you've entered those
tips.
So for example, at least the 216 that you need, you've got to
do a double verification and identify for the instrument
where those tips are sitting there.
And if you remember from the previous screen, if you wanted
to turn on the volume reagent, the check reagent volume portion
of this too, it will take that five minutes to make sure that
it's double checking for you what you have volume wise in the
various areas that are necessary.
So it does have those checks enabled for you and it helps you
to verify that as you walking through this process, Cindy.
So let's come out of this module and go back to that start
screen so that we can move on to the next portion of the workflow,
which would be the quantification workflow.
Similar to how we did the purification, set this up through
an option of the kit you would like to use.
It's really easy this time because this is set up just to be
used with our premium quantification kit, Quantifylet, Trio.
In the next line, you can do what we did at the purification
step, give this a run name of your own liking or leave it as the
default and then enter in the user name again so that we can
move on to the setup for your quantitation process here.
Now, this is where you get to make those same types of
decisions as you did on that first screen for purification,
but now for your quant setup.
And I believe that where we left off was a Kingfisher deep well
plate with your samples in after elution last time.
So let's pick that and assume that we're going to be using
the Quant Studio 5 system, but you do have the option to
switch to the 7500 real time PCR system if that's what the lab
chooses to use here.
Now, in order to tell the system what it is that you're
going to be processing in quantitation, you need to
again choose a file.
So let's choose that work list so that we have it loaded here
and you'll see that numbered in this scrollable work list from
1 through to 96 with some options at the top here for a
couple of controls that you're going to need to use for your
setup plate with a positive control and the NTC or the
no template control there.
Finally, in this setup portion, you get to choose if you want
the robot to create a new standard curve from the DNA
standard that's included with the Quant Triage Kit, you want to
use existing pre-prepared standard curves that you've saved
from a previous experiment or that you don't want to use a
standard curve at all for this experiment, perhaps you're
using that protocol in your lab with a virtual standard curve.
So we're going to ask it to create a new standard curve here
and it automatically knows then that you need to create that
for a five point standard curve.
You can easily switch this to a six point standard curve with
a click of a button here.
The same barcode scan capability is there too for you
which will ignore for the purposes of this.
And this is where I really enjoy this setup here.
You get then to choose if you would like from a series of
templates that are already preloaded and available for you.
A default five point standard curve
entered onto the plate setup for you with duplicates of each
one of your samples or you can move forward to a default
five point single sample quantitation plate setup here.
And there as you scroll through here, there's the same here
for your six point standard curves or a virtual standard
curve too.
So what I'm going to choose for the benefit of this demo is
the five points standard curve single sample plate setup
and apply that template to your output plate map here
so that it puts those samples into that plate map for you.
And then from here have another couple of options.
You can either use that as is or you can replace samples.
Let's say you don't want to process sample 85, but you'd
rather put a positive control of yours in that position.
You can drag and drop that sample and remove that target
from the plate, go back to your work list and simply drag
and drop a positive control into that position on the plate.
So you can remove any of the other samples that you wish
and replace them with samples from your work list as you wish
as you go through that sample work list there.
Now, what you'll notice is we had 96 samples,
but we're only processing 84 in this plate map here.
If you go to the very bottom of your work list,
you'll see that those samples are identified very clearly
by flashing red symbols around those samples.
Just to tell you, we know that these haven't appeared
on your plate map, not to worry.
What you can do is easily go to this export work list,
click that button and it automatically makes another work
list for you to come back and use so that you can process
the remaining samples.
So you're not going to miss utilizing all of those samples
should you wish to process them all.
Now, if you think that this is the type of plate setup
that you like or you want to make it a different way
for your ongoing use for other users in the lab,
you can actually save this, save this plate map simply
by entering a name for it and you put that as part
of the templates that are available to you
or any of your colleagues in the lab moving forward.
So you might have that as part of your SOPs.
From there, very simply you click continue
and you get to a screen that is now familiar to you
with the deck layout at the top.
And again, these areas here that tell you how much
of each of these samples or buffers need standards,
this DNA standard, for example, in position J
on the multi-tube adapter that sits in position 10
on your rack, on your deck there,
how much of that you need to add.
So 30 microliters of the DNA standard,
plus five empty tubes and positions one through five
highlighters and green here,
so that your standard curve samples can be made
in order to run this process for you.
So that's how you set up the deck ready
for your quantitation set up reaction,
to set up your plate for that.
Another area to point you to is the change in filtered tips
and they're now asking for 50 microlitre filtered tips
and you need 109 of those in these positions
of any of these positions eight here on the deck.
And as you would imagine, you need to be directed
to put your elution plate here in position four
so that those samples can be drawn from
in order to set up that quantitation plate.
So everything is intuitive as far as where it directs you
to put all of the reagents, labware,
and your samples in order to move forward with this.
Then you click continue again and the robot goes
about its business and produces for you an Excel file
as an output file to take forward to your quantitation
instrument and be able to run that quant reaction there.
And so hopefully that's easy and that's intuitive
and you can quickly work through where
and how you need to put your deck together in order
to get your quant plate set up in that manner.
And any thoughts on that ladies and any questions
about it as we get ready to move on to the final portion
of this demonstration?
- I had a quick question for people like me
who might forget one of these things to put on the deck.
Is there a check system throughout or in the beginning
when you say continue, go to the instrument?
Is there kind of a check system that says,
did you put this on area 10?
Did you put this for the tips in area eight?
Things something like that?
- When you press continue certainly for those tips
you'll be asked to verify where those are
and you will go through that process of confirming
that you have in the right position those items
and those components so that you can move forward
with this reaction, Kimberly.
Hopefully it's as intuitive to you as it is
and looks throughout the course of this demonstration.
So moving on to our last workflow
which is the amplification and normalization portions
of your setup.
We are able to go into these menus
and select from a drop down all of the kits
that we have available, global filer,
global filer IQC, verifiler, NGM direct,
Wi-filer plus and then a large reaction,
1000 reaction global filer kit two.
So I'm gonna choose the regular global filer 200 reaction kit,
give it a run name, leave it at the default
or change it should you wish to
and put my own username in there again.
Continuing on to the screen where you're able to now
make your selections in order to set up
the amplification reaction plate,
you'll be familiar again with this concept
and from there choosing what the input
from a drop down menu might be.
So a plate is the default but we put our illusions
into a Kingfisher deep well plate.
So I'm gonna choose that as there is indicated
from that menu and over here whichever CE instrument
you wish to use from our portfolio, the 3500 series,
the SEK Studio or the Flex series as well.
For today's demo, I'd like to use the SEK Studio 8 cap flex
genetic analyzer.
So it makes it really easy for you downstream.
Now in selecting the samples and the setup
of the reaction plate,
I'm gonna assume that you have the quantitation data
in a file, let's choose the original work list
from that file selection menu
and then the associated file that will allow you
to input samples with quantitation values
for this portion of the method.
Now when we go to our templates,
you will be able to choose
and the most appropriate template
or create your own with our assistance if you'd like.
We today are gonna choose not a duplicate sample one
but an eight cap single sample template
which I will apply.
And what that will do is take those samples across
to the reaction plate and the other items
that are displayed on the right hand side here
of your screen.
And let me go back to the work list
so that this stops scrolling and show you
that if you choose from here, edit again,
you can make changes to a couple of things
that are really interesting.
First of all, the global target concentration
for all of the samples.
Maybe you wanna set it at one nanogram
for all of your samples that you're processing.
You might wanna slide it up.
Maybe for some reason wanna do 1.3, 1.5,
anything between 0.1 and four nanograms
is available for you globally.
So if you set that there at one nanogram, that's great
or you can go to any sample, click on it
and you can enter for whatever reason you have
available to you a different target.
I'll put 0.8 nanograms for sample six in there,
submit it and the system will save that
and tell you what it's doing with that sample.
You can do that bespoke for each sample
or just leave it at the global concentration target there
as we've set.
Now from here, you'll see that those samples
are already pre-populated because of that template.
If you wanted to drag and drop out a sample
such as 82 and move it out of that plate
and save it for later, you can.
Perhaps you want to replace that with, for whatever reason,
sample 95.
If you can go to your work list, click on that,
drag it into that open position and drop it
and it will replace that sample into that position.
Now you'll see all of these red highlighted samples
are doing what we've looked at before,
telling you that they haven't been able to be
put onto this plate just because of real estate
and you can click again on this export work list button
to create a work list that will incorporate
those leftover samples onto a downstream work list.
If you would like to look at the details
of each one of these plates that are going to be utilized
on the instrument for making this reaction plate
the way that it needs to be, you have your input samples
that is your Kingfisher deep well plate
that has your original samples in it.
Then the dilution plate, this is what it's going to do
and what it's going to need for each one of those samples
in the dilution plate there.
And the details, if you just hover over any one of those cells
or sample numbers, you'll see what the details
of that dilution are based upon the quant value
that's been incorporated and imported into this
part of your workflow.
- I have a question about the dilution plate.
Can they be reused?
For instance, if we did the amp and say
that the electropharyngeal data looks a little bit funny
and we want to reamp, can we work off of the dilution plate
to reamp it or it's a whole new setup again?
- That's a great question.
You'll have that dilution plate available to you
and there's, I'm just hovering over one sample,
you'll see that you have more than enough volume there
to be able to use or even cherry pick out
and put in a new work list, those samples,
if you have a concern with one or two of those samples
and put it into a downstream work list
for using again, Kimberly.
So I hope that's a help to you
in order to be able to use that information
and take out any of those samples
and put them into a new place
should you need to use them
for a brand new amplification setup.
So from here, what we would do is click the continue button
and take you to that all familiar screen
and then going to that deck layout page
where again now it becomes the same process
that you've been used to on the previous steps
of seeing where everything needs to be on the deck
and from there, very simply click continue,
verify those same components again
and your system starts to run
and prepare those dilutions for normalization
and also the output reaction plate
that you can take off the instrument
and put directly onto your thermal cycler
and then take forward to process on your 3500 CE instrument
and that hopefully is as intuitive as it gets
in setting up those three real important portions
of your workflow within your lab
to save you the time and the processing necessities
that you need to do in order to get you
to this place efficiently and effectively.
Any thoughts or questions about that ladies?
- I particularly like the drag and drop part
of editing the plate
because I think along with many labs here
in the area that we have a soft a quant
allowance in our procedures.
So if there is a sample that is too low
or not worth going forward for DNA
that we won't continue it for applications.
So when we're doing the application setup,
as I saw that you can just remove that from the plate
and just simply put it in the trash bin.
So that's really easy.
Yeah, that looks like that.
I like that.
- And that's a good point Kimberly
and there's a little feature which is not contained
within the sample set that we've used today.
But if you try to amplify a sample
that you're not gonna be able to reach the target of
that you've set in that amplification plate,
the work list will actually and the plate map
will actually highlight it in orange
so that you know fine well that it's not going to do
what you're trying to do with that sample.
So you have that double bagging effect if you like
to make sure that you're safe
and that you understand what you're doing
with each one of your samples.
It'll do it on the plate map
and it will do it on your work list for you.
So again, that's a great feature of this software
to make it even easier for you to identify
those types of samples.
Do you think this will make things easier for you
in your lab throughout all of these workflows
and help you set up and claim back some of that time
that you could use better somewhere else?
- Absolutely.
I think we are going to love this.
And even from the validation and the implementation side,
I think it's gonna be a lot easier.
I'm already formulating what kind of worksheets we need
to create for analysts and to verify the steps
and this has reduced so many checks.
So it'll make that easier as well to develop a protocol.
- That's great to hear, Cindy.
Thank you for that feedback.
Really appreciate it.
I guess I really just need to ask,
what are you gonna do with all of this time
that you're gonna save?
(laughing)
- It allows us to focus on maybe some other things
in other areas of the laboratory or and TRs.
I mean, technical reviews.
That's always a big bottleneck for us
as that we cannot get to them
because we're processing.
- Excellent. That's great to hear.
Well, thank you so much for joining me today.
I hope it's been useful.
It sounds like it has and I'm glad that you're excited
to get this in your hands.
I know that you're gonna be doing that very shortly
but I wanna just tell you that I appreciate you joining me
for this reveal of this software
that's gonna enable your instrument to do so much more
that you've been asking for actually
and hopefully will make things so much more efficient
and effective for your important workflows
within your laboratory.
- Thank you.
Thank you, Dave. We're so excited.
We can't wait to get it online.
- Oh, likewise.
Well, we're looking forward to continuing
and partnering with you.
So thank you so much again for your time today
and good luck as you move forward
and utilize this in your successful work
within the San Mateo County Sheriff's Office,
Forensic Crime Lab.
We appreciate your partnership.
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