Watch how the Sacramento County Crime Lab DNA analysts Flex their Power in the unveiling of the new SeqStudio Flex Genetic Analyzer.
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[Music]
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I'm Nick Andrews, product manager at Thermafisher Scientific,
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part of the human identification team, or HID as it's known.
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Today we're here in sunny Pleasanton, California, the home of the HID Research
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and Development team.
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We have something super exciting to share with you today. We are ready to
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unveil the latest and
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greatest genetic analyzer, the Seek Studio Flex. Now you may know that the Seek
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Studio Flex has
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been available for the research community, but we're ready for forensic prime
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time. So today we have
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three forensic experts from the Sacramento County Crime Lab who are here to put
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it through its
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paces. They'll get to see all the greatest features like the four-plate deck
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with continuous plate
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loading, sample reprioritization, the integrated data collection software, and
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the remote monitoring
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and remote troubleshooting features. I know this instrument is going to blow
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them away and it's
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going to blow you away too. So let's go meet the team. I cannot wait to see
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what they think.
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My name is Ryan Nickel and I work for the Sacramento County Crime Lab. I'm a
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criminalist there and
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I'm also a crime scene lead at the laboratory. I'm Natalie Jones. I also work
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at the Sacramento
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County Crime Lab as a criminalist and I'm also the local codist administrator.
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I'm Danielle Frost.
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I'm also a criminalist at the Sacramento County Crime Lab and I'm in training.
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Thank you so much
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for introducing yourselves and thank you very much for coming in. This is great
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. You all seem to
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have a lot of different experiences so this is going to be a really exciting
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time. Just to confirm,
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you're all forensic scientists and none of you are paid actors. No, I'm not
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trying to say it.
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Right. So what do you actually know about the Sikh Studio Flex? It's been out
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for the research
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community for a while so have you heard anything about it? Nothing. Only the
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name which I saw in
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the email that we got. CE Instrument. Yep, that's right. It's our brand new
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latest and greatest
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genetic analyzer that we have. It got released for our research community a
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while ago and now we're
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ready to avail it for the HID market. So we want you guys to be the first look
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at this instrument.
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So we're the first forensic scientists to this. You're going to be the first
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forensic scientist
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in the world to touch this instrument. Wow, it's exciting. Well, then this is
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exciting.
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This is going to be exciting. It's cool. It's going to be great. So if you had
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a new CE Instrument
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for your lab, what would you want it to do? Would there be anything you'd be
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looking for?
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I would probably something along the lines of if one plate is running, if you
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could actually load
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a plate on while the other plate is running would be great. That would be a big
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help in our laboratory
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for sure. Glad you say that. I think it would be nice to be able to load more
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than two plates.
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Four, maybe six. That way we can get everyone at the lab working on at the same
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time and just
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turn the instrument on and let it go. I would love for the software to be
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really user-friendly and
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to be able to easily load on your plate and press buttons. Say go.
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And you mentioned that you were currently in training. So how has it been
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learning how to use
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CE in the application of forensic DNA? It's been challenging just learning
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memorizing the steps.
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There's so many steps that come with the CE in managing the software. So it's a
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question of
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where do I look for this button? It's kind of hidden away in this corner. So
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that's been difficult.
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Right. Yes. I know for my time in the lab. You all have 3500s in your lab,
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correct?
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Yes. So what do you like using about the 3500 or how has it helped you?
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I like the anode and cathode buffer that it's just you don't have to load it or
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make any
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mixture. It comes in a pre-made box. You can throw that right on. I also like
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the,
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it scans the polymer for us and tells us how many injections. So that's nice. I
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like that we have
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our lab uses 24 capillaries so we can get through a lot of samples pretty quick
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Yeah, we use USBs. So we have to go into the run room, load it onto the USB,
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take it back to our
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desk, load it into the software. So I hadn't thought about that but that would
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be nice if we could
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like remote into that computer from our desk, pull our data, put it right into
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the software.
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I would love that. Yeah. I'm sure actually other analysts that are, you know,
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we're allowed to work from home a couple days a week would actually like to
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remote in, get their
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data and actually analyze data from home. If you need some re-injections, you
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don't have to worry
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about re-plating when you come in the next day. I'd be cool. Can this
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instrument tell us at our
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desk that something's wrong? We can pop in there and fix it. Well, I don't want
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to give too much
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away but it might have some of these features that you've been looking for. I
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like it. I'm pretty
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happy that you brought these up but I think maybe we should probably get in
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there and actually see
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this instrument. All right. Let's see it. Cool. Let's do it.
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Okay. Oh Ryan, Natalie, Danielle, Yiga Beaver. I would very much like to
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introduce to you
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the new six new blocks. Wow. Very sweet. Yes. That is cool. No, can I have it?
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Yeah. How can we
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touch it? Go ahead. I had my phone. Now you can get in there. Like the looks
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very similar
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back there. Yeah. Can we take a closer look? Please. I'm assuming touch screen.
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I want to
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know how many plates. Can I touch the screen? Can we open it? Yeah. Boom. Four
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plates guys.
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Four. You can see the drawers unlocked. Go ahead. To oh, they're there. They're
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there.
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Yep. That's fun. So you can load while it's running. Yes.
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Continuous plate loading. Sample re-prioritization. So you can load a plate. It
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could be injecting.
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You could then load another plate. You could say my injections more important.
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You could put that
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to the top of the list and it will take that plate. You could have four plates
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in there.
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When one plate is finished, you could open that drawer to take it off and there
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's a new spot open
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again. You could maybe wait until the end of the day, load four plates at once
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and it can just run
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all night and then you can come back into data in the morning. I know one of
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your concerns might
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have been about, well, what happens if there's an injection failure or
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something like that?
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But this also has a remote monitoring. So you can get alerts at your computer.
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You can get up on
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your phone. You can even do re-injections from your phone with this instrument.
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So if you are working
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remotely, you can do that. Yes. And for those of you who maybe use a 31-30 back
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in the day,
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while you have the barn doors, this instrument has the same type from there.
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Very cool. Easy to get
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in there. Obviously your oven door. You may not be able to newly designed array
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as well, so it's
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actually easier to install than even the 3500. I love that. It looks easier too
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. You can kind of
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see just where the little buttons are there. Pop in out. Exactly. So can I open
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the drawer right
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now to the instrument? Yeah, as long as that screen says the drawer is unlocked
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, you can open that drawer
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at any point. Go ahead. My question was, is there like an arm that kind of
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grabs those plates and
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takes it up to be analyzed? That's exactly right. So the arm will pick up the
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plate and move it up
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to where the capillaries are, so you can actually do the injection itself.
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So that drawer is unlocked at any point during the run, so you can load plates.
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The only time it
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would be locked is when an injection is in place. Just for safety reasons, you
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've got high voltage
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running through there. But otherwise you can load plates on there. That screen
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will also tell you
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when you have plates that are present on there, so you can see what is linked
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and you know if there's
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available space on it. And do this plates set in or do they clip in? They just
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sit on top of there.
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So as long as you put them in that plate cradle, then they just sit in there
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and they wait for the
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arm to come and pick them up. Very cool. What about the runtime? It's actually
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about the same as the
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3500, so it's kind of around the same time that you had before. A couple of
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other features while we
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have the drawer open, there's also an integrated barcode scanner in there. So
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if you use barcoated
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plates, it can read that so that you actually know what you're linking and you
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can verify it.
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As before, you just have to make sure that you put the plate in the right place
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This time you don't. I see two USB ports right there. Is that to bring in our
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data and it automatically
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kind of populates into the screen there? So we knew that there's obviously a
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lot of different
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options that you can have when you want to transfer data. This instrument does
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have cloud
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connectivity and local area network as well. So you can network the instrument
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on your local
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area network in the lab. You can set up your plates from your office and you
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can have those plates
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loaded directly onto the instrument through a piece of software called plate
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manager,
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which we'll show you in a bit. And then you could also do a USB, so you could
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put it into like your
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standard CSV or text file, load it onto the instrument, or you could do it
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through the cloud.
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So you could use plate manager on the cloud, set up your plate and it will
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remotely send that
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plate to the instrument itself. That's cool. A bunch of different options.
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One thing I did want to do is introduce you to two of our R&D scientists who've
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been working
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really hard on the validation of this instrument. They are going to help us set
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up a run and get
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the instrument going and teach you how to use the instrument thoroughly. So
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what do you say we go
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meet them? Yeah. All right. Hi everybody, my name is Dan Sunil. I'm a staff
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scientist and
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a summer fisher. I've been working on this project for over one year. So today
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I'm going to show you
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how to use the plate manager. That's a software used for creating your files
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for running the
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samples on six U2FLEX. So we have two different versions. One version is on the
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cloud. Another
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version is on the desktop. So this is the version on cloud. So you can create
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your file from the
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scratch by clicking on this guy here, or you can open a file which has been
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saved on cloud,
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or from your computer. Or if you want to use a recently used file, you can
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click on this one.
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You can check, see whether it's correct or not. If everything is correct, so
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you can send this to
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the machine directly. You can choose multiple instruments at the same time and
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click on OK.
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So then this file would be sent to your instruments. Or you can just choose one
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of them. So like
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today, I'm going to just send this one to this instrument. So after you see it,
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you just click
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OK. So now the file is on your instrument. You are ready to run your sample on
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the instrument.
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And also I'm going to show you how to create a file using the plate manager. I
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will be using
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the desktop version today. So I'm going to show you how to create a plate file
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from the scratch.
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So to do that, just click on this one here. Then you get all of these things by
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default.
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You can change your name here. You can change the name of the file. Or you can
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just use the default
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file name. If you say OK, all the parameters here are correct. So you click on
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Next.
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Then you can click on the carbon. You want to put your samples in. And then you
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can come here.
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From here, you choose the injection protocol. So today, I'm going to show you
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how to
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choose this one. That's for the J6 die. So after you click on that, see all the
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other parameters,
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you know, show up here. After that, you click on here. So then you can put the
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name of the files
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in there. So what I do, I just, you know, I have prepared everything. So I just
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copy the thing here
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and then paste it to the software. Sample name, I click on this one and control
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V.
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So then the file names are pasted here. And also you can put the panel names
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here.
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So these are the panel names. All of them here are used globe file, IQC panel.
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So click on the
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software here. So then you get to this panel. Okay, so you click on the first
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one.
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You click on control V here. So in the file, these are the panel names. And
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then I put the
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k-link here. I highlighted everything here and then control C.
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And put it into the first custom fields. Then control V. Okay, after that, you
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go here, you save it.
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And then it's saved. After you saved, you can put send it to the instrument. Or
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you can export it
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into USB drive. So I can export it to either my computer or USB drive. So save.
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Now it's saved in this USB drive. And then I'm ready to use it.
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Is the computer attached or connected to the instrument at all?
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Yeah, so this computer is connected to the instrument through Wi-Fi. Gotcha.
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Yeah, nice. And at our lab, we use an Excel program.
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Yeah. Our sample names and information. So we would be able to export that in
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like a
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CSV file and then load it into the software rather than manually setting up our
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plate.
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Yeah, so you can do that. So basically after you set up the plate using plane
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manager,
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or you have a CSV file installed in the on your computer or USB drive.
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So instead of a computer, can you use your phone to do this?
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Yeah, you can use your smartphone. Do the same thing. You can monitor your rung
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and also you can unlink or link your plate. If you found that after you go home
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or if you are somewhere else far, far away, if you just thought, "Oh, I made a
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mistake."
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So you can make the revision of your protocol using your cell phone or your
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computer remotely.
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Nice. That's really cool. A good feature.
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Yeah. Now the plate is in the same location. You don't even need to come here
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to unlink the plate.
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You can just use that with your... Or set my injection before his.
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I also really loved that each injection was a different color. That was very
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pleasing to the eye.
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Yeah, exactly. Me too.
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So if there's somebody at your lab that always thinks their case is the most
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important and wants
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to jump in front of everybody all the time, is there a way to prevent plates
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from getting
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bumped to the front? I think that would be a very good feature. But all these
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things should
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be tracked in the SAE feature. So we could know who jumped in front of my run.
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Got it.
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Hi, my name is Jimmy Lee. I am a staff engineer at Thermo Fisher. I will be
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showing you the 6-3D
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of flex. So this is the new instrument. So I'll have Ryan come and play with
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the instrument if you
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want to. Sure. All right. So if you want to load, I know Leonton helps you set
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up a plate.
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Right? So here I'm going to hand you that plate. Okay. You can open the drawer.
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So there's positions A, B, C and D. Already two have been filled. So you can
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put it in C or D.
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Okay. I'm going to go with D. Oh, I already... Oh, ZZ. Slide it in. There you
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go. It will lock
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once you close it. But now you can link your plate, which has already been
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loaded on by Leonton.
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So click link plate. Yep. Go to my instrument. And it's right there, the demo 8
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-cap.
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And then you can check all of the properties. So you click on application.
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Click on application.
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Oh, there it is. Okay. ZZ is already on HID 96-wool plate 3600 meter pop-4.
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Click done.
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Go to plate screen. And here we're going to do an injection from column two.
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Okay. Yeah. If you
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want to see what it is, you can go and highlight it. And those are your
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parameters. And you can
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click on the pencil button. And then you can scroll and see all the
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configurations. Nice.
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I stand there. Okay. For the most part, you have your J6 sample in there. Yep.
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Click done.
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And when you're ready to run, click start. Start around. Yeah.
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Is there a way to check the names of the samples that are in there? Go back to
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that pencil.
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You can go to sample name. Click on multiple. And here is where you can enter
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all of your names in.
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Oh, gotcha. Austin's already pre-named him here. Right. There's the eight. And
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then you go to sample
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type and change the... You can go there. And then he's the first one to a
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little glatter.
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The rest are sample. Gotcha. Okay. Cool. Yeah. And then...
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And then... Start. Start around. There you go. Right on.
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You'll do some pre-checks to make sure the consumables are not expired. And
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they'll give you an estimated
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end time. And there it goes. Nice. That starts up really fast. Yeah, it did.
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Did it have to pre-heat?
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So if you didn't preheat your oven, then it will have to pre-heat. You can
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actually do that
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before you run. If you hit that speedometer symbol on the top. Yep. If you
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scroll to the left,
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there is a pre-oven option. But it's already heating up right now. So it's
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disabled. Okay. So you don't have to worry about that. But you see the oven
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temperature is already
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at 31 degrees. So... Do you guys recommend pre-heating? Or is it not necessary?
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If it's already warmed up,
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it'll run faster. How long to preheat? Maybe like 10 minutes before you start
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your run. Yeah.
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I like that the things you can't select are grayed out and things you can are
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blue.
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So you can also turn on the LED to highlight some of the instrument stuff. So
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...
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There. Turn on some of the consumables. Since it's running, you can't really
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open the door.
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But there's that CBC buffer right there. It's going with the polymer pouch and
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then the ABC
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buffer. Same array. Slightly different from the 3500, but similar format here.
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So this is the 24
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cap array. Okay. So you open the oven and you just easily install any one that
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you want to.
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Okay. Did you change anything on the consumables as far as like they can be
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only be on the instrument
20:09
for two weeks? Yeah. So if you go back to the right on the screen, it shows you
20:13
all of your
20:14
status that the consumables. So the capillary, how many injections that's left,
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the polymer,
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and the installation date and the expiration date as well as your buffer. And
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here's your spatial
20:25
calibration, your remaining injections, and then all the calibrations that were
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done for your
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die sets that you can run. And then on this side, you should see some of the
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maintenance stuff that
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needs to be done. Some of them you might need a software update from time to
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time, but it'll tell
20:38
you when you need to do all your maintenance. Okay. And like the wizards kind
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of for that stuff.
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Yeah. Good. Yeah. You want to go to that, the X out of that? Sure. Click on
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action. Click on
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maintenance. Yep. And then maintenance wizards. So here you have a list of
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anything you want to do
21:00
for maintenance. You can change your array, change your polymer type, change
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your buffer,
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change your polymer. And each of them have a video embedded so you can actually
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watch some of them
21:08
for a little bit. So now, like I showed you before, you can actually run
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multiple plates at a time.
21:14
So click home. So now the, it's unlocked so you can open it up. So you put that
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in position to see.
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All right. Oh, lock again. But now you can link a plate. So create a new plate
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file.
21:33
And here you can name your plate. So just click plate name. Yep. Type whatever
21:39
you
21:39
today's day. Okay. Blade two. All right. Enter. Go to application type.
21:47
Like that. Change it from sequencing to XID. Yeah. Done. Yeah. Done. Go to your
21:55
plate.
21:57
And then you can click on the pencil button. Click on injection protocol. One
22:03
time. Yep. And then
22:04
you can pick which die set you want to run. Okay. And then you can change any
22:10
of the
22:10
problems. So this injection protocol free populates these fields for you. If
22:13
you want to do any of
22:14
the custom ones, you can change them here. So done. Done. And start. Start. So
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will it run in the order
22:24
that you set it? So this will run after that first one is done. If you wanted
22:29
to change it,
22:30
since it's already started, you can't do that. But you go to run queue, you'll
22:33
see the order of
22:34
things that will be done. So I can take plate two and go right. Right. It's
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like top of the list.
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Right. So these ones are completed. So plates D is running. So your plate C is
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going to run
22:46
afterwards. So it's in queue. And it'll show you the estimated start at end
22:51
time. Okay. So you have
22:53
to remember where you loaded it. Exactly. Okay. So you can click close. And if
23:01
these since these are already done, you can actually look at some of the data
23:03
on there. So you click on
23:04
the screen. Click real sample list. So that's what we ran. This is just the
23:10
installation run.
23:11
So you click done. Click on action. So you can either unlink, but you want to
23:18
look at the data,
23:19
click on the green icon. And that's what we were with run on that plate. So you
23:24
can use this
23:25
e-gree or the screen to like scroll through, expand that blue bar if you want
23:28
to. That's cool.
23:31
No. Oh. Click on any of those menu, the bullet point buttons.
23:37
And then you can select dies that you want to see. Oh.
23:40
Yep. So you just turned out blue. Oh, turn them off. Okay. Yep. So now you're
23:47
just looking at
23:49
the size standard orange. Oh, there you go. And then when you want to bring the
23:54
samples back in,
23:55
just click on the color again. Yeah. Right. And on the right side, there's
24:00
another option where you
24:03
can zoom in and. Oh, there you go. And then the middle button. It's fine. It's
24:13
your EPT. So it
24:14
shows you the record of all of your, your, your run, nice to the oven
24:18
temperature,
24:19
your current, your voltage throughout your entire run. So same thing, same
24:24
touch face,
24:25
touch me in the face. So, and then when you're done with that, just click done.
24:28
Click done.
24:30
I like that black background. It's so much easier to see the colors than the,
24:35
than the white.
24:36
Yeah. So let's say you want to run another plate. These all are filled. You can
24:40
unlink a plate by
24:41
just pressing B. Do you want to try it? Okay. Sure. I'll link the plate. It's
24:46
going to confirm that
24:46
you want to do that. So now you can open the drawer, remove the plate. And if
24:52
you have another
24:53
one ready to go, you can pop it. Oh, and it shows that it's removed. It will
24:57
sense the plate right
24:58
over there. Yep. It's all I could, I'll take that. Okay. So now you can, you
25:02
know, leave it there,
25:03
load another plate or, you know, awesome. Have it on standby. Yep. Very cool. I
25:08
noticed this is
25:09
your computer now. You're not hooked up to a computer. So currently, we, to do
25:15
like a reboot
25:16
of the system every two weeks, we'll shut down, shut down, restart, restart. So
25:20
you don't need to
25:20
do that for these? Yeah. If you want to restart for any reason, you can just
25:24
power off when no
25:25
place are on there, not running and power back on. Is that something
25:28
recommended or can we just
25:29
leave it on? You can leave it on. Yeah. There's no reason I would need to turn
25:33
it off though.
25:34
Nice. Nice. Yeah. We talked a little bit earlier about having the computer
25:39
in the instrument hooked up to Wi-Fi and being able to control it from your
25:43
phone and everything.
25:44
Forensic labs are always concerned about security. So I wanted to ask about
25:48
that.
25:49
Right. So these instruments can be controlled with SAE. So like the security
25:53
audit and the
25:54
e-signature functions. So if you have it on the network, if anyone logs in,
25:58
they have to have their
25:58
own account login. If they want to start a run, they have to have permission to
26:02
sign off. If you
26:03
don't want to have it on a network, you can have a local computer attached to
26:07
the instrument,
26:08
and it's also controlled by SAE. Wi-Fi free, just local area, just within house
26:13
. So no internet needed.
26:15
Yeah. And then as soon as this run is done, we can access it on the computer,
26:20
any computer,
26:21
with a Wi-Fi on our phone. Yeah. You can do remote access. I do have it on my
26:27
phone. It can
26:28
monitor run and I can show it yet as well.
26:37
So from our remote monitoring app, you can remote monitor your run. So here it
26:41
has a run that's
26:41
already completed. Click on your raw plot. And now Ryan, you can scroll the
26:46
data on the phone,
26:48
just like you would on the flex. Okay. You can see all the peaks. Yep. Yep. And
26:54
you can click on
26:55
different capillaries on top. And then you can filter by color. And then just
27:01
...
27:02
Let's do... Yeah. Apply. There you go. There's your size standard. Yeah.
27:08
Scroll and go to all the capillaries. Yep. Okay. And it will save your
27:14
preference on color. So...
27:16
All right. Nice. There you go. So what's coming off the instrument is being
27:22
correctly...
27:25
screamed to your phone. Exactly. Yep. Like it. Thank you.
27:35
So we'll have a look at the six-year flex a bit. I know we talked about how the
27:44
consumables are the
27:45
same, except from the array. So I just wanted to show you really quickly how
27:48
you can change the
27:49
array in that sort of process. But you could open it up these big barn doors.
27:53
And then if you want
27:55
to open up the array, I mean, this will get you to do it. Just show you how
27:58
easy it is. Open the
28:00
array door. Unscrew the detection cell. Loosen the cap bundle. There you go.
28:12
And then loosen the
28:14
bottom door. It's down here. There you go. And you can slide that out slightly.
28:21
And then you can just use this little handle here and just pull that out of
28:28
there.
28:29
And it will hold it in place. Let's remove it. Great. Where am I? So the very
28:38
nice thing about
28:39
these new arrays are they have to make it easier to do it one-handed. They lock
28:45
in place. So you can
28:46
hold it to and you can install the array one-handed. So it'll stay like this
28:50
when you want to load it
28:51
back into the instrument. Just slide it in place like that. And then you can
28:57
release it. Feed it
29:00
into the bottom. The detection window is automatically there. It's in the right
29:03
place. The instrument
29:04
knows where it is. So you can just tighten everything back up again. Close the
29:08
doors.
29:09
Tighten your football. The feral at the end. And that's it. That's changing the
29:18
array.
29:18
Easy, easy. Wow. Very easy. The nice thing about this instrument, the very cool
29:24
thing is,
29:25
and when you change your array, what do you normally have to do after that?
29:28
You run a special, a spectral and a spatial. Right. So you run the spatial
29:32
because that's how the
29:33
instrument knows where each of the capillaries are. You run the spectral
29:36
because that's teaching
29:37
the instrument the die set that you're going to be using for that. Right. And
29:40
to make sure it's applied
29:41
to this new array. The nice thing about this instrument, you only need to run
29:45
that spectral once.
29:47
That's crazy. Like throughout the entire life of the instrument.
29:51
Correct. The instrument will remember the spectral you have run as long as you
29:55
're running the same
29:56
die set for that chemistry. It will continue to apply that every time you
30:00
change the array.
30:02
That's really cool. It's incredible. Yeah. That's amazing. I'll get them.
30:05
Remember
30:05
it. It makes sure your data is still there. The only time you will ever need to
30:08
run the spectral
30:09
is if you change die sets. So a different type of chemistry. Or you are
30:13
troubleshooting. Wow.
30:15
So I can save you a lot of time running this instrument. Especially it's one of
30:21
those things.
30:22
It's like, I feel like we do it, but not enough to really like learn it well
30:27
every time you do it.
30:28
So it's we never have to learn it again. Exactly. Break out the manual every
30:32
time.
30:33
Every single time. And the other thing. So obviously a lot of these things on
30:37
the instrument,
30:37
you don't have to do that often. So what we do have on this instrument as well
30:41
is to help you
30:42
is called the learning center. So if you go to actions and then learning center
30:48
from here,
30:49
you have helpful videos that you can run that will walk you through when you
30:54
need to do
30:55
different steps on the instrument. So if you want us to learn about how to set
31:00
up a run on the instrument.
31:01
And it will take you through all the steps you need to on how to run and set up
31:14
a run.
31:15
Wow. That's cool. For me, I learned a lot better with videos too. Like, hey,
31:20
here's how you do this.
31:21
Instead of like, you know, reading something that makes it a lot, a lot more
31:25
difficult to be like,
31:26
oh, take the plate and put it here or do this. It's like, oh, video shows you
31:30
exactly how to do it.
31:31
So now we have everything for a visual kinesthetic learners, no matter what you
31:34
do.
31:34
Yep. This is really great for new analysts also. New analysts, maybe analysts
31:41
who haven't
31:41
run the CE in a while, you know, you're just coming back into the lab. It's
31:45
just making it so that
31:46
it's easy. It's approachable and you just know what you're doing. Yeah. Yeah.
31:49
So you can always feel
31:50
confident when you run the CE in a flex. So back to the, you know, kind of old
31:57
school almost like
31:58
barn doors feels nice. But I also like the familiarity with it too. It has kind
32:03
of this,
32:04
you know, you haven't changed everything inside. We don't have to learn an
32:07
entirely new instrument.
32:09
It's just almost like an upgrade to the instruments with a whole bunch of cool
32:14
features.
32:15
All right, guys. We've had a really exciting day and an action-packed day
32:25
learning all about
32:26
the CE to do your flex. I really just want to know what you guys think about it
32:29
. It's awesome.
32:30
I think the design is really sleek. It's user-friendly. You can take your data
32:35
on the go.
32:36
Yes, I love the like onboard computer. So you don't have to restart and link
32:43
these two separate
32:44
things and that you can remote in and from home or from your desk, monitor your
32:49
run,
32:50
set re-injections, put your plate before your co-workers. Exactly. Yeah. And I
32:56
even heard you
32:56
ask some really important questions about data security and stuff while you
32:59
were there. I mean,
33:00
that is something that we know is a huge challenge for forensic labs. The world
33:05
is moving connectivity
33:06
and cloud-based things. And that's why at Thermofisher, we have a group that is
33:09
dedicated to testing
33:11
vulnerabilities on our software and our cloud-based systems. And we have teams
33:16
that are actually
33:16
there helping you so you can bring online and work with your IT groups within
33:20
your lab to figure out
33:21
what is possible to do within your lab. Because what we're finding is there's a
33:25
lot of stuff
33:25
that we can actually do and still be very secure. The old-school methods of
33:29
actually using USBs
33:30
is not the secure method anymore. It's actually having connectivity with
33:34
encryptions and secure
33:36
passwords. So it's going to be really exciting for the future. And this
33:39
instrument is definitely
33:40
going to take us there. I also like the footprint of this instrument. You know,
33:45
for something that
33:45
can hold four plates and kind of run all these things, it's about almost the
33:50
same size as the 3500.
33:51
So it's taken up a nice small amount of space. You know, as long as it's deep
33:57
enough at your lab,
33:58
you can get a couple of these, I think. And you don't need that control
34:02
computer either,
34:03
if you don't need to. So in terms of actual bench real estate, you're a lot
34:07
less. Yeah.
34:09
And being able to put another plate in the queue while one is running, that
34:12
feature I absolutely
34:13
love. I've spent a lot of time waiting for my co-workers to finish up their run
34:18
before I can
34:19
even start prepping my plate. And how do you think that this would benefit you
34:22
in your lab?
34:23
New instruments or kind of new technology comes out like once every five years
34:27
or so I feel like,
34:28
and this is just kind of taking us to that next step of, you know, the fact
34:32
that it has the Wi-Fi
34:33
capability or the cloud-based capability, it just kind of has that feel of, hey
34:39
, we are getting
34:40
into that next generation of instrumentation. So I like it. You know, it's
34:45
staying current with
34:48
everybody else's kind of phones and computers and what we're used to instead of
34:54
running on
34:54
some old instruments. Right. Exactly. And if your lab is not ready for that,
34:58
you can also do it
34:59
the standard way as well. So it's very versatile in that sense. But it's going
35:04
to be ready for
35:04
the future when we're there. Yeah, the fact that you still have the USB, you
35:07
know, people like to
35:08
get in their steps still. So it's like, hey, you don't have to use your phone.
35:12
Go and get those steps
35:14
in, walk to the instrument again, take it off and take it back to your desk.
35:18
And what do you think
35:19
about the onboard learning center? Do you think that will help you in the lab?
35:23
I do. Because I know
35:25
sometimes when you have to like put new polymer on and you haven't had to do
35:29
that in eight months,
35:31
I have to pull out that manual and figure out how to reload my polymer or
35:35
something. So now I can
35:36
just play, see how to do it, pop it on. I don't have to worry about it. Yeah,
35:40
the fact that you can
35:41
actually pause the video too and do that while you're doing it. The doors are
35:47
separate from the
35:48
computer screen. So you can just pause it, do that, okay, click play and
35:53
continue on. It's nice.
35:54
And watching the video of it happening in real time is a lot easier than having
35:59
to read through
36:00
the wizard like we do now. So that's really nice. And what about the startup
36:04
sequence?
36:05
Have you guys think about that? I think it's great because currently, like I
36:09
said earlier with the
36:11
computer next to your instrument, you have to turn this off, turn this off,
36:16
turn this on, turn this
36:17
on, wait for a green light, open your software. So now it's just one button,
36:22
turn the instrument on
36:23
and you're ready to go. And what do you think about the array? This was
36:26
absolutely amazing. So can I?
36:28
Yeah, please. So you literally just squeeze that and it releases. That's really
36:35
cool. That was
36:36
something I didn't know that I needed. Yeah, exactly. No more fumbling around
36:40
with the detection cell
36:41
window, trying to get that in place with the magnets and then making sure it's
36:45
just right.
36:46
Not breaking it. Not breaking the array. That's key as well. But yeah. Yeah, I
36:52
was always worried.
36:53
I'm like, "Oh, capillary needs to be changed." I'm like, "Maybe I'll just
36:56
pretend I didn't see it on
36:58
the instrument. Someone else will change it because it's like this thing is
37:01
like, you know, kind of
37:02
all over the place. So it's nice that it's everything's kind of in place. You
37:06
know, a couple clicks,
37:07
a couple knobs to turn and it's in and ready to go. Yeah, you can do it 100.
37:13
No more three hands and tape kneaders. I know we've had an action-packed day.
37:18
It has been super
37:19
exciting from our side. Then we're Fisher Scientific has loved having you here.
37:22
So thank you so much
37:23
for taking the time. It has been great. I really hope you got a lot out of it
37:27
and I can't wait until
37:28
the next video. Thanks so much for having us. This is wonderful. I had a blast.
37:32
You were the first
37:33
accredited forensic scientist to do a run on the HID version of the Seac Studio
37:38
Flex. This is great.
37:40
Thank you guys so much. Thank you. Thank you.
37:48
[end]
37:54
[ Silence ]